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Copper and zinc utilization in elderly adults

D M Burke, F J DeMicco, L J Taper

    Journal of Gerontology
    |September 1, 1981
    PubMed
    Summary

    Elderly adults showed negative zinc balance despite adequate copper intake. Higher zinc levels reduced copper retention, indicating nutrient antagonism. Hair analysis suggested sufficient long-term mineral intake.

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    Area of Science:

    • Human Nutrition
    • Mineral Metabolism
    • Gerontology

    Background:

    • Copper and zinc are essential trace minerals with complex interactions.
    • Nutrient balance and body composition are critical health indicators in elderly adults.
    • Previous research suggests potential antagonism between copper and zinc intake.

    Purpose of the Study:

    • To investigate the effects of varying zinc intake on copper and zinc balance in elderly adults.
    • To assess copper and zinc status through excretion and hair content.
    • To explore potential interactions between copper and zinc metabolism.

    Main Methods:

    • A 30-day metabolic study involving elderly adults.
    • Administration of 2.33 mg copper and either 7.80 or 23.26 mg zinc daily.
    • Measurement of daily mineral excretions and analysis of hair mineral content.

    Main Results:

    • Subjects maintained a positive copper balance but a negative zinc balance.
    • Higher zinc intake significantly reduced copper retention, confirming nutrient antagonism.
    • Hair zinc and copper levels were higher in females and indicated adequate long-term intake.
    • Recumbent length was found to be greater than standing height in the elderly.

    Conclusions:

    • High zinc intake can negatively impact copper retention in the elderly.
    • Zinc and copper metabolism are interconnected, with potential for antagonistic effects.
    • Hair mineral content may serve as an indicator of long-term nutrient status in older adults.
    • Recumbent length measurement warrants further investigation for accurate height assessment in the elderly.

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