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Updated: Aug 18, 2026

Pentylenetetrazole-Induced Kindling Mouse Model
Published on: June 12, 2018
Modification of amygdalo-cortical evoked potentials by kindling and pentetrazol-induced generalized convulsions in
Abstract:
Amygdalo-cortical pathways were studied in control cats, kindled cats and pentetrazol-injected cats by the evoked potential method. An increase in amplitude of suprasylvian cortical evoked potentials to stimulation of the amygdala was observed in the kindled group and in the pentetrazol group. Moreover, evoked potentials to stimulation of the amygdala appeared at the sigmoid gyrus after generalized convulsions in the kindled group and after pentetrazol in the other group. These modifications were permanent in the kindled group while they were only transient in the pentetrazol group.
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