Novel source of ubiquitous phthalates as analytical contaminant

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The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission.

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Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

Frontiers in pharmacology·2025

The angiotensin II type 2 receptor antagonists, PD123,319 ((S-( +)-1-[(4-(dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid), EMA300 (5-(2,2-diphenylacetyl)-4-[(4-methoxy-3-methylphenyl)methyl]-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-6-carboxylic acid) and EMA401 ((3S)-5-(benzyloxy)-2-(2,2-diphenylacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid), evoke pain relief in a varicella zoster virus-induced rat model of neuropathic pain.

Inflammopharmacology·2025

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine.

Frontiers in pharmacology·2024

Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials.

Discover oncology·2022

Bacterial nanocellulose as a drug delivery system for local anesthetics: A novel approach for non-invasive pain management.

Journal of pharmaceutical sciences·2026

Biowaiver monograph for immediate-release solid oral dosage forms: Dabigatran etexilate.

Journal of pharmaceutical sciences·2026

Glycerol-rich vesicular matrices as an effective oral platform for valsartan: Box-Behnken optimization and ex vivo/in vivo evaluation.

Journal of pharmaceutical sciences·2026

A combined approach for full API particle size distribution characterization in nasal spray suspensions based on their dissolution behavior.

Journal of pharmaceutical sciences·2026

Nitrosamines and their precursors in pharmaceutical packaging and potential contamination for stability chambers.

Journal of pharmaceutical sciences·2026

Key strategic considerations for pooling multiple drug substance batches in biopharmaceutical drug product manufacturing.

Journal of pharmaceutical sciences·2026

The AGO2-ATOX1 axis exacerbates inflammation in a mouse sepsis model.

Central-European journal of immunology·2026

Synthesis and Characterization of 2-(1-Hydroxyethyl)Promazine Sulfoxide-d4 HCl as an Internal Standard for the Accurate Quantitation of 2-(1-Hydroxyethyl)Promazine Sulfoxide in Equine Urine.

Journal of labelled compounds & radiopharmaceuticals·2026

Rapid and validated LC-APCI-MS/MS method for determination of N-nitroso vonoprazan in pharmaceutical products.

Journal of chromatographic science·2026

Detection of trace formaldehyde in beef tripe using doping-assisted positive photoionization high-field asymmetric waveform ion mobility spectrometry.

Analytical and bioanalytical chemistry·2026

Chromatogram-level FID/MS data fusion in comprehensive two-dimensional gas chromatography enables robust quantitative volatilomics: Application to extra virgin olive oil.

Journal of chromatography. A·2026

SPR-UPLC-QTOF/MS-GNPS-Guided Discovery of Hypermonol J as a Novel Tumor Necrosis Factor-Binding Small-Molecule Lead for Inflammatory Storm Intervention.

MedComm·2026

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Novel source of ubiquitous phthalates as analytical contaminant

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An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy.

The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission.

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine.

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Synthesis and Characterization of 2-(1-Hydroxyethyl)Promazine Sulfoxide-d4 HCl as an Internal Standard for the Accurate Quantitation of 2-(1-Hydroxyethyl)Promazine Sulfoxide in Equine Urine.

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Novel source of ubiquitous phthalates as analytical contaminant

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