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Related Experiment Videos

A new ventricular-performance variable using electrocardiogram and carotid pulse contour derivative

M A Frey, R M Siervogel

    Japanese Heart Journal
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

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    Measuring ventricular performance non-invasively can be challenging. The study proposes Q-MAX, derived from electrocardiogram and carotid pulse, as a reliable alternative to the pre-ejection period (PEP) for assessing cardiac function.

    Area of Science:

    • Cardiology
    • Biomedical Engineering
    • Physiology

    Background:

    • The pre-ejection period (PEP) is a standard non-invasive measure of ventricular performance.
    • Accurate PEP measurement requires simultaneous recordings that are often difficult to obtain.
    • Alternative non-invasive indices are needed for reliable cardiac function assessment.

    Purpose of the Study:

    • To compare two alternative non-invasive indices, DAR and Q-MAX, with PEP.
    • To evaluate the correlation of these indices with PEP, heart rate, and blood pressure.
    • To assess the ease of monitoring and measurement precision of the alternative indices.

    Main Methods:

    • Compared PEP with DAR (carotid pulse derivative ratio) and Q-MAX (time from Q-wave to peak dD/dt).
    • Measured indices in 35 subjects (17 female, 18 male) in supine and head-up tilt positions.

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  • Examined correlations with age, heart rate, blood pressure, and changes after propranolol administration.

    • Main Results:

    • DAR showed poor correlation with PEP.
    • Q-MAX was easier to monitor and more reliably measured than PEP.
    • Q-MAX correlated with PEP in supine and tilted positions and similarly with heart rate and arterial pressure.
    • Both PEP and Q-MAX prolonged after propranolol administration.

    Conclusions:

    • Q-MAX is a viable and potentially more practical alternative to PEP for assessing ventricular performance.
    • Q-MAX offers a reliable, non-invasive method for monitoring cardiac function.
    • Further validation of Q-MAX in diverse populations and conditions is warranted.