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[Intracardiac hemodynamics and myocardial contractile function indices in chronic ischemic heart disease]
Insights
Echocardiography reveals that chronic ischemic heart disease (IHD) significantly impairs left-ventricular function. Reduced ejection fraction and myocardial contractility indicate early disease progression and reduced heart muscle efficiency.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Chronic ischemic heart disease (IHD) affects cardiac function.
- Assessing myocardial contractility is crucial for IHD management.
Purpose of the Study:
- To evaluate left-ventricular function in IHD patients using echocardiography.
- To identify key echocardiographic indices for early IHD manifestation.
Main Methods:
- Echocardiography was performed on 51 patients with chronic IHD.
- Key parameters assessed included left-ventricular volumes, ejection fraction (IF), velocity of circulatory shortening (Vch), and structure functioning intensity (SFI).
Main Results:
- Progressive IHD led to increased left-ventricular volumes and decreased IF and Vch.
- IF and Vch are sensitive indicators of early myocardial contractility disorders.
- Reduced SFI in severe IHD correlated with increased myocardial mass and impaired cardiac function.
Conclusions:
- Echocardiographic indices like IF and Vch are vital for detecting early IHD-related contractility issues.
- In severe IHD, reduced SFI suggests impaired myocardial function due to pathological involvement.
Abstract:
Echocardiography was used in the examination of 51 patients with chronic ischemic heart disease (IHD) without accompanying hypertension and congestive circulatory insufficiency. With gradual advancement of the disease, a significant increase in left-ventricular volumes during the systole and diastole was recorded as well as a decrease in the ejection fraction (IF) and velocity of circulatory shortening of the myocardial fibres (Vch) in slight variations of the stroke volume. The IF and Vch were the most characteristic indices for appraising the early manifestations of myocardial contractility disorders. The index of left-ventricular structure functioning intensity (SFI) was used to characterize the functional state of the heart muscle. In patients with a severe course of the disease, SFI was found to be reduced because of an increase in the myocardial mass. The developing damage hypertrophy, however, did not provide for full compensation of left-ventricular function and was attended by a reduction of the indices of contractility and pump function of the heart. This provides the grounds for the assumption that the reduction of SFI in patients with severe IHD is associated with exclusion of part of the myocardium involved in the pathological process from effective functioning.