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Tidal expiratory flow patterns in airflow obstruction

M J Morris, D J Lane

    Thorax
    |February 1, 1981
    PubMed
    Summary
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    Analyzing tidal expiratory flow patterns offers a new quantitative method for assessing airflow obstruction. This method

    Area of Science:

    • Pulmonary Physiology
    • Respiratory Medicine

    Background:

    • Airflow obstruction is a significant respiratory condition.
    • Current methods for assessing airflow obstruction can be complex.
    • Tidal breathing patterns may offer a simpler diagnostic approach.

    Purpose of the Study:

    • To evaluate the tidal expiratory flow pattern as a quantitative measure of airflow obstruction.
    • To compare the expiratory flow patterns of healthy individuals with those having various lung disorders.

    Main Methods:

    • Analysis of expiratory flow patterns against time in 99 subjects.
    • Inclusion of normal volunteers, patients with dyspnea, restrictive lung disorders, and airway obstruction.
    • Quantification of the rapid rise to tidal peak flow using percentage of volume expired (delta V/V) and percentage of expiratory time (delta t/t).

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    Main Results:

    • Airflow obstruction demonstrated a quadrilateral expiratory flow pattern, distinct from the sinusoidal pattern in healthy subjects.
    • Both delta V/V and delta t/t indices showed significant correlation with conventional measures of airway obstruction.
    • The observed pattern in quiet breathing resembles a forced expiratory maneuver, potentially due to dynamic compression or altered lung recoil.

    Conclusions:

    • Tidal expiratory flow pattern analysis is a viable quantitative method for assessing airflow obstruction.
    • The distinct pattern and derived indices offer potential for early and accessible diagnosis.
    • Understanding the mechanisms, including dynamic compression, is crucial for interpreting these findings.