Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stage A prostate cancer from pathologist's viewpoint

M Golimbu, J Glasser, R Schinella

    Urology
    |August 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    PM289, a synthetic CB2 in vitro receptor agonist, modulates morphine-induced antinociceptive effect and withdrawal syndrome in an animal model of osteoarthritic pain.

    Neuropharmacology·2026
    Same author

    Early ethanol exposure during gestation and lactation disrupts gut integrity and enhances ethanol intake in C57BL/6 mice offspring.

    Alcohol (Fayetteville, N.Y.)·2026
    Same author

    Mitochondrial dynamics and sex-specific responses in the developing rat hippocampus: Effect of perinatal asphyxia and mesenchymal stem cell Secretome treatment.

    Biochimica et biophysica acta. Molecular cell research·2024
    Same author

    Stromal interstitial keratitis in a patient with COVID-19.

    Journal francais d'ophtalmologie·2022
    Same author

    Corneal perforation triggered by the use of urine therapy drops: Management with scleral and amniotic membrane grafts.

    Journal francais d'ophtalmologie·2021
    Same author

    Trends in corneal transplantation in a single center in Barcelona, Spain. Transitioning to DMEK.

    Journal francais d'ophtalmologie·2019
    Same journal

    Editorial Comment on "A Histopathologic Assessment of Prostate Ductal Anatomy in Relation to Micro-Ultrasound".

    Urology·2026
    Same journal

    Same-Day Discharge Following Multiport Robot-Assisted Simple Prostatectomy: A Prospective Feasibility Study of Outcomes, Costs, and Post-Discharge Healthcare Utilization.

    Urology·2026
    Same journal

    Extended versus Standard Lymph Node Dissection at the Time of Radical Cystectomy for Bladder Cancer.

    Urology·2026
    Same journal

    Intractable Epistaxis and Severe Hypertension in a Young Woman.

    Urology·2026
    Same journal

    A 53-Year-Old Man with Elevated PSA and a Cystic Pelvic Lesion.

    Urology·2026
    Same journal

    Low-Grade, Papillary Bladder Tumors A plea for in-office fulguration.

    Urology·2026
    See all related articles

    Pathologists generally agree that a 5 mm diameter or three tumor-containing chips define early-stage prostate cancer (A-1). However, examination techniques for prostatic specimens vary significantly among practitioners.

    Area of Science:

    • Uropathology
    • Surgical Pathology
    • Prostate Cancer Diagnosis

    Background:

    • Accurate staging of prostate cancer is crucial for treatment decisions.
    • Early-stage prostate cancer (Stage A) requires precise pathological assessment.
    • Standardization of pathological examination for early prostate cancer is lacking.

    Purpose of the Study:

    • To determine the consensus among pathologists regarding criteria for Stage A-1 prostatic carcinoma.
    • To investigate the routine pathological examination methods for prostatic specimens.
    • To identify variations in the assessment of focal adenocarcinoma in prostatic tissues.

    Main Methods:

    • A survey was distributed to 465 pathology departments in the United States.
    • Questions focused on the maximum allowable diameter of focal adenocarcinoma in enucleated specimens.

    Related Experiment Videos

  • Questions addressed the maximum number of tumor-containing chips for transurethral resected specimens.
  • Inquiries were made regarding routine pathological examination protocols for prostatic specimens.

    • Main Results:

    • A majority of pathologists consider a 5 mm diameter as the maximum for a focal (A-1) lesion in enucleated specimens.
    • The consensus for transurethral resected specimens is a maximum of three chips containing tumor for A-1 classification.
    • Pathologists' techniques for examining prostatic specimens, especially larger ones, show considerable diversity.
    • Most pathologists examine all chips from specimens <10 Gm, but only 12% do so for specimens >10 Gm.

    Conclusions:

    • While there is some agreement on size criteria for early prostate cancer, pathological examination methods are highly variable.
    • The diversity in techniques may impact the consistency and accuracy of prostate cancer staging.
    • Further standardization of pathological examination protocols for prostatic specimens is warranted.