Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vesicourethral smooth muscle: function and relation to structure

O P Khanna, E J Barbieri, M Altamura

    Urology
    |August 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mathematics and Measurement.

    Journal of research of the National Institute of Standards and Technology·2016
    Same author

    Disordered eating behavior and mental health correlates among treatment seeking obese women.

    La Clinica terapeutica·2015
    Same author

    Tricyclic structures in medicinal chemistry: an overview of their recent uses in non-CNS pathologies.

    Mini reviews in medicinal chemistry·2008
    Same author

    Tachykinin receptors and gastrointestinal motility: focus on humans.

    European review for medical and pharmacological sciences·2008
    Same author

    Maturation of fish erythrocytes coincides with changes in their morphology, enhanced ability to interact with Candida albicans and release of cytokine-like factors active upon autologous macrophages.

    Immunopharmacology and immunotoxicology·2005
    Same author

    [Effects on function of human lymphocytes exposed to electromagnetic fields with a frequency from 1,500 to 2,000 MHz].

    Giornale italiano di medicina del lavoro ed ergonomia·2003
    Same journal

    Preventing Postpartum Pelvic Floor Dysfunction: Clinical Evidence and Policy Gaps in U.S. Coverage of Pelvic Floor Muscle Therapy.

    Urology·2026
    Same journal

    Editorial Comment on "Through the Eyes of the Applicant: A Qualitative Study of the Urology Residency Match".

    Urology·2026
    Same journal

    Editorial Comment on "A Histopathologic Assessment of Prostate Ductal Anatomy in Relation to Micro-Ultrasound".

    Urology·2026
    Same journal

    Same-Day Discharge Following Multiport Robot-Assisted Simple Prostatectomy: A Prospective Feasibility Study of Outcomes, Costs, and Post-Discharge Healthcare Utilization.

    Urology·2026
    Same journal

    Extended versus Standard Lymph Node Dissection at the Time of Radical Cystectomy for Bladder Cancer.

    Urology·2026
    Same journal

    Intractable Epistaxis and Severe Hypertension in a Young Woman.

    Urology·2026
    See all related articles

    This study reveals three distinct muscular systems within the rabbit vesicourethral structure. These systems, differentiated by their responses to acetylcholine and norepinephrine, highlight complex functional organization.

    Area of Science:

    • Urology
    • Pharmacology
    • Anatomy

    Background:

    • The vesicourethral structure's muscular organization and innervation are crucial for urinary function.
    • Understanding the differential roles of acetylcholine and norepinephrine is key to elucidating bladder and urethral physiology.

    Purpose of the Study:

    • To investigate and compare the effects of acetylcholine and norepinephrine on smooth muscle strips from the rabbit bladder body, base, and proximal urethra.
    • To delineate distinct functional muscular systems within the vesicourethral complex based on pharmacological responses.

    Main Methods:

    • Isolated smooth muscle strips from rabbit bladder body, bladder base, and proximal urethra were subjected to pharmacological stimulation.
    • Functional responses to acetylcholine and norepinephrine were recorded and compared across different anatomical regions.

    Related Experiment Videos

    Main Results:

    • Three distinct muscular systems were identified based on differential sensitivity to acetylcholine and norepinephrine.
    • System 1: Acetylcholine-sensitive detrusor, deep bladder base, and longitudinal urethral smooth muscle.
    • System 2: Norepinephrine-sensitive detrusor, superficial bladder base, bladder neck, and part of longitudinal urethral smooth muscle. System 3: Circular urethral musculature, independent of the detrusor.

    Conclusions:

    • The rabbit vesicourethral structure comprises at least three functionally distinct muscular systems.
    • These systems exhibit specific sensitivities to neurotransmitters, suggesting specialized roles in micturition and continence.
    • The circular urethral musculature operates as a separate entity from the detrusor muscle complex.