[Clinical effectiveness of specific hyposensitisization in treating bronchial asthma depending on the time of its...

During the period 1974-1979, an allergologic study was carried out on 7228 patients from six districts of North-East Bulgaria. Specific hyposensibilization was conducted to 3312 patients, the effect having been followed up in 2004 of them. Young patients with infectious-allergic forms predominated, with a moderately severe course and duration from 2 to 5 years. The specific hyposensibilization was conducted according to the officially adopted method, the effectiveness determined via clinical criteria. The specific hyposensibilization effect develops slowly, the percentage of favourable effect increasing with long-term treatment -- good results were attained after one year treatment in 10.97 per cent, with a two-year treatment -- in 42.56 per cent, with three-years -- 54.47 per cent, with four years -- 61.27 per cent.