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Orally administered tetracycline for phlyctenular keratoconjunctivitis
American Journal of Ophthalmology
|August 1, 1981
Summary
Oral tetracycline effectively treated recurrent nontuberculous phlyctenular keratoconjunctivitis in six patients, offering rapid symptom relief and disease arrest. This safe alternative to corticosteroids showed minimal recurrence, making it valuable for resistant cases.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Nontuberculous phlyctenular keratoconjunctivitis (KCN) can cause progressive corneal damage.
- Recurrent KCN poses challenges, often requiring alternative treatments.
Observation:
- Six patients with recurrent KCN, corneal vascularization, and scarring were treated with oral tetracycline.
- The treatment aimed to manage symptoms and prevent disease progression.
Findings:
- Oral tetracycline provided rapid symptom relief and appeared to arrest the disease progression.
- No significant complications were observed during tetracycline treatment.
- Only one mild recurrence (conjunctival hyperemia) was noted post-treatment.
Implications:
- Oral tetracycline is a safe and effective therapeutic option for resistant and recurrent KCN.
- It serves as a viable alternative to topical corticosteroids, especially for patients with corticosteroid-induced complications.