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Related Experiment Videos

Ventricular fibrillation during programmed ventricular stimulation: incidence and clinical implications

S R Spielman, A Farshidi, L N Horowitz

    The American Journal of Cardiology
    |December 1, 1978
    PubMed
    Summary

    Programmed ventricular stimulation rarely induced ventricular fibrillation (VF). VF occurred in 3.3% of patients, exclusively with double extrastimuli in those with suspected or documented VF/VT, suggesting a specific risk group.

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    Area of Science:

    • Electrophysiology
    • Cardiology

    Background:

    • Programmed ventricular stimulation (PVS) is used to assess arrhythmia susceptibility.
    • Ventricular fibrillation (VF) is a life-threatening arrhythmia.
    • Identifying patients at risk for VF is crucial for effective management.

    Purpose of the Study:

    • To investigate the incidence and characteristics of ventricular fibrillation induced by programmed ventricular stimulation.
    • To determine the specific stimulation parameters associated with VF induction.
    • To identify patient subgroups at higher risk for inducible VF.

    Main Methods:

    • Prospective study of 300 patients undergoing PVS.
    • Utilized single and double ventricular extrastimuli during various cardiac rhythms.
    • Analyzed induction of ventricular fibrillation and related clinical characteristics.

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    Main Results:

    • Ventricular fibrillation occurred in 10 (3.3%) of 300 patients.
    • VF was only induced by double ventricular extrastimuli, not single extrastimuli or pacing.
    • All VF events occurred in patients with documented or suspected ventricular tachycardia/fibrillation.
    • Seven patients experienced VF during sinus rhythm or pacing; three during ventricular tachycardia.

    Conclusions:

    • Ventricular fibrillation is uncommon during PVS.
    • VF induction is specific to double extrastimuli in susceptible patients.
    • PVS can identify patients at risk for spontaneous VF/VT episodes.