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Inbreeding, mortality and genetic load in families with congenital heart diseases
Acta Anthropogenetica
|January 1, 1981
Abstract:
A total of 93 cases of congenital heart diseases (CHD) were studied for the effects of inbreeding on the incidence of these diseases. Sib mortality and genetic load in families with CHD were estimated. This study indicated (1) involvement of recessive genes in causation of CHD, (2) lack of inbreeding effects on sib mortality in CHD, and (3) the nature of genetic load to be segregational.