Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Smoking and arterial reconstruction

R M Greenhalgh, S P Laing, P V Cole

    The British Journal of Surgery
    |September 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Maximum bite force at age 70 years predicts all-cause mortality during the following 13 years in Japanese men.

    Journal of oral rehabilitation·2016
    Same author

    Longitudinal relationship of severe periodontitis with cognitive decline in older Japanese.

    Journal of periodontal research·2016
    Same author

    Lymphangiography by radiological methods.

    The Journal of the Faculty of Radiologists. Faculty of Radiologists (Great Britain)·2014
    Same author

    Self-reported measures for surveillance of periodontitis.

    Journal of dental research·2013
    Same author

    Serum antibody to Porphyromonas gingivalis in chronic kidney disease.

    Journal of dental research·2012
    Same author

    Relations of serum ascorbic acid and α-tocopherol to periodontal disease.

    Journal of dental research·2011

    Higher carboxyhaemoglobin (COHb) levels, linked to smoking, predict failure in reconstructive arterial surgery. Patients should cease smoking before surgery to improve outcomes for arterial disease.

    Area of Science:

    • Vascular Surgery
    • Cardiovascular Disease
    • Biochemistry

    Background:

    • Stenosing arterial disease poses significant risks.
    • Identifying preoperative risk factors is crucial for surgical success.
    • Biochemical markers may predict outcomes in vascular reconstruction.

    Purpose of the Study:

    • To compare preoperative risk factors in patients with arterial disease against controls.
    • To evaluate the association between preoperative risk factors and the success of arterial reconstruction.
    • To determine if specific biochemical markers predict failure in reconstructive arterial surgery.

    Main Methods:

    • Measured fasting serum levels of triglyceride, cholesterol, lipoprotein, uric acid, fibrinogen, and carboxyhaemoglobin (COHb) in 64 patients.

    Related Experiment Videos

  • Compared patient levels to age- and sex-matched healthy controls.
  • Assessed arterial reconstruction outcomes clinically and via Doppler pressure measurements, categorizing into success and failure groups.

    • Main Results:

    • Patients with arterial disease had significantly higher levels of triglyceride, cholesterol, lipoprotein, uric acid, and COHb compared to controls.
    • No significant differences in most risk factors were found between reconstruction success and failure groups.
    • Carboxyhaemoglobin (COHb) levels were significantly higher in the group with reconstruction failure.

    Conclusions:

    • Elevated carboxyhaemoglobin (COHb), a marker of smoking, is associated with poorer outcomes in reconstructive arterial surgery.
    • Preoperative smoking cessation is recommended to improve the success rates of arterial reconstruction.
    • COHb may serve as a valuable predictor for reconstructive arterial surgery outcomes.