Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The lung in immunoblastic lymphadenopathy

S L Bradley, D E Dines, P M Banks

    Chest
    |September 1, 1981
    PubMed
    Summary

    Immunoblastic lymphadenopathy (IBL) is diagnosed via lymph node biopsy and presents with systemic symptoms and organ enlargement. Treatment involves steroids, with chemotherapy if steroids fail, and careful diagnosis of pulmonary infiltrates.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Purulia Dispensary, Manbhoom: Clinical Notes on Some Surgical Cases.

    The Indian medical gazette·2017
    Same author

    A novel highly differentially expressed gene in wheat endosperm associated with bread quality.

    Scientific reports·2015
    Same author

    A robust and well shielded thermal conductivity device for low temperature measurements.

    The Review of scientific instruments·2014
    Same author

    Thermal conductivity of Ho2Ti2O7 along the [111] direction.

    Physical review letters·2013
    Same author

    Multiband order parameters for the PrOs4Sb12 and PrRu4Sb12 skutterudite superconductors from thermal conductivity measurements.

    Physical review letters·2008
    Same author

    Gastrointestinal lymphoproliferative disorders.

    Histopathology·2007

    Area of Science:

    • Immunology
    • Oncology
    • Pulmonology

    Background:

    • Immunoblastic lymphadenopathy (IBL) is a severe condition characterized by systemic symptoms including fever, malaise, cough, dyspnea, lymphadenopathy, and hepatosplenomegaly.
    • Key laboratory findings include hypergammaglobulinemia, and imaging may reveal interstitial pulmonary infiltrates, mediastinal adenopathy, and effusions.

    Purpose of the Study:

    • To outline the diagnostic approach and treatment strategies for immunoblastic lymphadenopathy.
    • To highlight the challenges in differentiating disease-related pulmonary infiltrates from infection or chemotherapy-induced changes.

    Main Methods:

    • Diagnosis is established through lymph node biopsy.
    • Treatment involves an initial moderate dose of steroids, with escalation if necessary.
    • Combination chemotherapy (cyclophosphamide, vincristine, prednisone) is reserved for steroid-refractory cases.
    • Diagnostic evaluation of pulmonary infiltrates may require transbronchoscopic or open-lung biopsy.

    Main Results:

    • The study reviews patient cases and previous reports to inform treatment recommendations.
    • Steroid therapy is the primary treatment modality.
    • Chemotherapy is effective when steroids fail to induce remission.
    • Distinguishing the cause of pulmonary infiltrates is crucial for appropriate management.

    Conclusions:

    • Immunoblastic lymphadenopathy requires prompt diagnosis via biopsy and a stepwise treatment approach.
    • Steroids form the cornerstone of initial therapy, followed by chemotherapy if needed.
    • Pulmonary complications necessitate careful diagnostic workup to guide treatment decisions.

    Related Experiment Videos