Gel chromatography for control purposes of human albumin preparations

Information on molecular composition of human albumin preparations is important for characterization of these protein mixtures. Permeation chromatography in gel columns is best suited for separative analysis with respect to time consumption and experimental and instrumental expenditure. Standardization, precision and reproducibility of this quality control method have been especially considered in our investigations and the best conditions for practical performance and evaluation have been established. Results will be discussed in comparison to those of sedimentation analysis in the ultracentrifuge.