Related Experiment Video
Updated: Aug 12, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Abstract:
The recent advent of high resolution chromosome techniques for the study of neoplasia has conceivably expanded the scope of cancer cytogenetics, making feasible the detection of chromosomal defects in most neoplasias. Because of the usefulness of the new technology, the Standard Chromosome Nomenclature has been extended to give a unified numbering system to the fine bands observed and to maintain a simple system for the description of previously undetectable defects and the more precise delineation of chromosomal rearrangements.
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When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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