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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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Related Experiment Video

Updated: Jul 9, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
07:35

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Published on: June 23, 2015

Cystic adventitial disease

J D Terry, J R Schenken, M R Lohff

    Human Pathology
    |July 1, 1981
    PubMed
    Summary

    Cystic adventitial disease is a rare cause of peripheral vascular insufficiency. Surgical resection of popliteal artery cysts is an effective treatment, especially when atherosclerosis is absent.

    Area of Science:

    • Vascular Surgery
    • Medical Imaging

    Background:

    • Cystic adventitial disease (CAD) is a rare condition causing peripheral vascular insufficiency.
    • It involves a mucinous cyst within the arterial wall, leading to lumen compromise.

    Observation:

    • Two cases of popliteal artery CAD treated with surgical resection are presented.
    • Angiographic findings suggestive of CAD include a lack of generalized atherosclerosis.

    Findings:

    • Surgical resection with graft interposition was the chosen therapy for both popliteal artery cases.
    • This approach effectively addressed the lumen compromise caused by the adventitial cysts.

    Implications:

    • CAD should be considered in cases of unexplained peripheral vascular insufficiency.

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  • Characteristic angiographic findings can aid in diagnosis, differentiating it from atherosclerosis.
  • Surgical resection is a viable treatment option for symptomatic CAD.