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Related Experiment Videos

Ascending spinal pathways mediating somato-cardiovascular reflexes

J W Kozelka, J M Chung, R D Wurster

    Journal of the Autonomic Nervous System
    |April 1, 1981
    PubMed
    Summary

    Spinal somatic afferent pathways influence cardiovascular responses during exercise. Lesions in specific spinal pathways altered heart rate during treadmill running, suggesting somato-autonomic reflexes are involved in exercise-related cardiovascular adjustments.

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    Area of Science:

    • Neuroscience
    • Cardiovascular Physiology
    • Exercise Physiology

    Background:

    • Somatic afferent fiber activation in cats influences cardiovascular parameters via distinct spinal pathways.
    • Dorsolateral sulcus (DLS) pathways mediate sympathetic cardiovascular responses to somatic afferent stimulation in dogs.

    Purpose of the Study:

    • To investigate the role of spinal somatic afferent pathways in cardiovascular adjustments during exercise.
    • To determine if DLS and dorsolateral funiculus (DLF) pathways are involved in exercise-induced cardiovascular responses.

    Main Methods:

    • Anesthetized and conscious dogs were used to study cardiovascular responses.
    • Dogs were trained to run on a treadmill (all 4 legs or hindlegs only) while monitoring blood pressure and heart rate.
    • Lesions were made in the DLS and DLF to assess pathway involvement.

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    Main Results:

    • Lesions in the DLS and DLF significantly altered heart rate responses during treadmill running on all 4 legs.
    • These findings indicate that spinal pathways play a role in mediating cardiovascular changes during physical activity.

    Conclusions:

    • Somato-autonomic reflexes, conducted through spinal pathways like the DLS and DLF, are implicated in cardiovascular adjustments during exercise.
    • The study highlights the contribution of the somatosensory system to autonomic control during physical exertion.