Related Experiment Video

Updated: Aug 15, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

The genetic basis for piebald patterns in cattle

T A Olson

    The Journal of Heredity
    |March 1, 1981
    PubMed

    More Related Videos

    Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing08:39

    Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing

    Published on: September 1, 2017

    Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish07:16

    Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish

    Published on: March 1, 2022

    Related Concept Videos

    Pedigree Analysis01:35

    Pedigree Analysis

    Overview
    Epistasis01:39

    Epistasis

    In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
    Pedigree Analysis01:35

    Pedigree Analysis

    Overview
    Incomplete Dominance01:43

    Incomplete Dominance

    Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
    Background and Environment Affect Phenotype02:27

    Background and Environment Affect Phenotype

    Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
    An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
    Epistasis Analysis01:09

    Epistasis Analysis

    Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...