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Anthelmintic efficacy fenbendazole paste in equines

F S Malan, R K Reinecke, R C Scialdo

    Journal of the South African Veterinary Association
    |June 1, 1981
    PubMed
    Summary

    A single dose of fenbendazole (FBZ) paste effectively treated common equine parasites in horses. This study confirms FBZ's high efficacy against various gastrointestinal nematodes and pinworms.

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    Area of Science:

    • Veterinary Parasitology
    • Equine Medicine
    • Pharmacology

    Background:

    • Gastrointestinal nematodes and pinworms are common parasites in horses, causing significant health issues.
    • Fenbendazole (FBZ) is a broad-spectrum benzimidazole anthelmintic used in veterinary medicine.
    • Assessing the efficacy of FBZ against specific equine parasites is crucial for effective treatment protocols.

    Purpose of the Study:

    • To evaluate the efficacy of a single oral dose of fenbendazole (FBZ) paste at 7.5 mg/kg body mass in horses.
    • To identify the specific genera and species of equine parasites susceptible to FBZ treatment.

    Main Methods:

    • A single oral dose of fenbendazole (FBZ) paste at 7.5 mg/kg body mass was administered to horses.
    • Parasite efficacy was assessed against adult stages of various nematode genera and species.
    • The study involved an initial group of 5 horses, with results confirmed in an additional 12 horses.

    Main Results:

    • Fenbendazole (FBZ) demonstrated high efficacy against adult Cyathostominae subfamily nematodes (Cyathostomum, Cylicostephanus, Cylicondontophorus, Poteriostomum, Cylicocyclus, Triodontophorus, Oesophagodontus).
    • FBZ was also highly effective against adult Oxyuris equi, Strongylus vulgaris, Strongylus equinus, and Probstmayria vivipara.
    • In a larger group of horses, FBZ at 7.5 mg/kg was highly effective against Parascaris equorum, Craterostomum, and Gyalocephalus.

    Conclusions:

    • A single oral dose of fenbendazole (FBZ) paste at 7.5 mg/kg is highly effective for treating common equine gastrointestinal nematodes and pinworms.
    • FBZ provides broad-spectrum efficacy against a wide range of economically important equine parasites.
    • These findings support the use of fenbendazole as a key anthelmintic in equine parasite control programs.

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