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Nucleolar changes in aging and autogamous Paramecium tetraurelia
Mechanisms of Ageing and Development
|July 1, 1981
Abstract:
A significant loss in nucleolar volume density (proportion of nuclear volume occupied by nucleoli) occurs in the macronucleus as clonal age increases, which suggests an age-correlated loss of ribosomal RNA synthesizing capacity. In the macronuclear fragments of cells undergoing autogamy, however, a significant gain in nucleolar volume density takes place.