[Use of structure-activity analysis in toxicology]

An account is given of principles and methods of quantitative structure-action analysis which have promising applications in toxicology. Particular reference is made to the development of active principles with low toxicity for warm-blooded animals, early assessment of toxicity of recently synthetised or envisaged compounds of one substance class of which the toxicity of some agents has already become known, and appraisal of unspecific toxic effects.