Isomorphous and anaplastic (polymorphous) oligodendroglioma

The problem of the astrocyte-like cells and giant cells in oligodendrogliomas is discussed, basing on morphological data of 22 tumours diagnosed as isomorphous, anaplastic and polymorphous type of oligodendroglioma. Multinucleated cells are characteristic features for polymorphous type of oligodendroglioma and the origin of multinucleated Langhans-like cells caused by a virus factor is proposed.