Cryotherapy of prostate cancer

Area of Science:

• Urology
• Oncology
• Surgical Oncology

Background:

• Prostate adenocarcinoma is a common cancer in men.
• Radical prostatectomy and radiation therapy are standard treatments.
• Cryosurgery offers an alternative for localized prostate cancer.

Purpose of the Study:

• To evaluate the efficacy and safety of cryosurgical destruction for primary prostate adenocarcinoma.
• To assess outcomes including tumor destruction, morbidity, and mortality.

Main Methods:

• Perineal cryosurgery was performed on 215 patients with localized prostate cancer (Stage B-D).
• Follow-up included clinical assessment for tumor recurrence and obstructive symptoms.
• Data on survival, local recurrence, and complications were collected over a 12-year period.

Main Results:

• 74% of patients achieved no clinical evidence of tumor in the prostatic fossa post-cryosurgery.
• Minimal need for transurethral surgery for obstructive symptoms was observed.
• Low morbidity and mortality rates were reported.

Conclusions:

• Cryosurgery is an effective method for local destruction of prostate cancer.
• The procedure demonstrates a favorable safety profile with limited complications.
• Cryosurgery presents a viable treatment option for select prostate cancer patients.