Hodgkin's disease -- analysis of fifty-three autopsy cases

Eight-eight autopsy cases originally diagnosed as Hodgkin's disease (HD) were reevaluated, and 53 cases were obtained as HD. Fifty three cases with HD were composed of 47 males and 7 females and 52 cases had an active disease. Frequencies of 4 subtypes such a lymphocytic predominant, mixed cellularity, lymphocytic depletion, and nodular sclerosis were found to be 24, 54, 14, and 6%, respectively at biopsy and 12, 38, 44, and 6%, respectively at autopsy, showing transition of subtype in HD. The manner of organ involvement, deviation of histologic figures between nodes and/or other organs, associated diseases including non-bacterial inflammation of lung, amyloidosis and secondary malignancy and differential diagnosis of HD from the confusing diseases observed in our series were described.