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Crystalline inculsion in myxoid liposarcoma
Acta Pathologica Japonica
|July 1, 1981
Summary
Electron microscopy revealed unusual crystalline inclusions within the granular endoplasmic reticulum of myxoid liposarcoma cells. Similar structures in normal cells suggest a potential functional origin unrelated to adipose tissue tumors.
Area of Science:
- Cell Biology
- Electron Microscopy
- Oncology
Background:
- Myxoid liposarcoma is a soft tissue tumor.
- Electron microscopy is used to study cellular ultrastructure.
Observation:
- Amorphous electron-dense material and crystalline inclusions were observed in the granular endoplasmic reticulum of myxoid liposarcoma cells.
- These inclusions exhibited transversal striations and were associated with round electrodense bodies.
Findings:
- The observed crystalline inclusions share similarities with structures found in normal vertebrate and plant cells.
- The presence of these inclusions is not exclusive to adipose tissue tumors.
Implications:
- The findings suggest that these inclusions may originate from a general cellular function rather than being specific to myxoid liposarcoma.
- Further research is needed to elucidate the precise functional role of these crystalline structures in various cell types.