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Transient diffuse computed tomographic scan enhancement in multifocal seizures

H S Schub, P A Ahmann, J R Steele

American Journal of Diseases of Children (1960)

|September 1, 1981

Summary

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Transient diffuse cortical enhancement on computed tomographic scans may occur in infants with multifocal seizures. This finding, similar to abnormalities in asphyxiated infants or child abuse victims, warrants further investigation.

Area of Science:

Neurology
Pediatric Neurology
Neuroradiology

Background:

Previous studies noted transient focal brain scan abnormalities in patients experiencing focal seizures.
Understanding imaging findings in pediatric epilepsy is crucial for diagnosis and management.

Observation:

A 1-year-old infant presented with repetitive multifocal seizures.
Computed tomographic (CT) scans revealed transient diffuse cortical enhancement.

Findings:

The observed diffuse cortical enhancement on CT scans in this infant with multifocal seizures is a notable neuroradiological finding.
This pattern of enhancement shares similarities with abnormalities seen in asphyxiated infants and cases of child abuse.

Implications:

Related Experiment Videos

The findings suggest that diffuse cortical enhancement on CT scans can be associated with non-focal neurological events in infants.
Further research is needed to differentiate seizure-related enhancement from other causes like hypoxic-ischemic injury or non-accidental trauma.
This highlights the importance of correlating imaging findings with clinical presentation in pediatric neurology.