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Evaluation of a computerized drug interaction screening system
American Journal of Hospital Pharmacy
|April 1, 1981
Summary
A computerized drug interaction screening system effectively identified potential drug interactions in a hospital setting. Pharmacists
Area of Science:
- Clinical Pharmacy
- Health Informatics
- Pharmacology
Background:
- Drug interactions pose a significant risk to patient safety.
- Computerized systems can aid in identifying potential drug interactions.
- Pharmacist intervention is crucial for managing identified interactions.
Purpose of the Study:
- To evaluate the effectiveness of the Pharmacy Automated Drug Interaction Screening (PADIS) system.
- To assess the clinical significance of detected drug interactions.
- To determine physician response to pharmacist recommendations.
Main Methods:
- A 100-day study evaluated PADIS in a community hospital.
- All non-pediatric patients were included (34,564 patient days).
- Potential interactions, their types, and physician responses were recorded.
Main Results:
- 1219 potential drug interactions were detected.
- Only 9.5% were deemed clinically significant.
- Pharmacists resolved 51% of interactions; physicians altered therapy in 82% of remaining cases.
Conclusions:
- The PADIS system is effective in detecting drug interactions.
- Pharmacist evaluation and physician collaboration improve patient safety.
- Computerized screening systems enhance drug safety protocols.
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