Wagner's vitreoretinal degeneration

Four members of a black family with findings of Wagner's vitreoretinal degeneration are described in this paper. All present with the classical findings of an optically clear vitreous and pigment abnormalities of the fundus varying from fine perivascular to dense peripheral pigment clumping. In addition, the characteristic associated findings of high myopia, gluccoma, presenile cataract formation, choroidal atrophy, and retinal detachment are documented. To our knowledge, we believe these to be the first cases of Wagner's disease to be presented in a nonwhite pedigree.