Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Necrotizing anaerobic infections

J K Bocking, R L Holliday, J H Duff

    Canadian Journal of Surgery. Journal Canadien De Chirurgie
    |September 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Septicemia.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Canadian critical care society.

    Canadian Medical Association journal·2010
    Same author

    Re-expansion pulmonary edema after repair of a missed diaphragmatic hernia.

    Canadian journal of surgery. Journal canadien de chirurgie·2001
    Same author

    Soft-tissue images. Insulinoma.

    Canadian journal of surgery. Journal canadien de chirurgie·2000
    Same author

    Nothing new on appendicitis.

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·1995
    Same author

    Attitudes toward trauma care of surgeons practising in Ontario.

    Canadian journal of surgery. Journal canadien de chirurgie·1995

    Severe necrotizing anaerobic infections, including gas gangrene and necrotizing fasciitis, often result from minor trauma. Early surgical debridement is crucial for treating these high-mortality infections.

    Area of Science:

    • Infectious Diseases
    • Surgical Pathology

    Background:

    • Severe necrotizing anaerobic infections present a significant mortality risk.
    • These infections encompass conditions like gas gangrene, necrotizing fasciitis, and nonclostridial myonecrosis.

    Purpose of the Study:

    • To review cases of severe necrotizing anaerobic infections.
    • To identify common antecedents, locations, clinical findings, and outcomes.
    • To evaluate treatment strategies for these infections.

    Main Methods:

    • Retrospective review of 17 cases.
    • Data collected from Victoria and University hospitals, London, Ontario (1975-1977).
    • Analysis of infection antecedents, affected sites, clinical signs, microbial findings, and mortality.

    Related Experiment Videos

    Main Results:

    • Minor trauma was the most common antecedent.
    • Scrotum and perineum were frequently involved sites.
    • Edema, skin tenderness, and induration were prevalent local findings.
    • Mixed infections were predominant; Clostridium sp. pure growth occurred in only 3 cases.
    • Overall mortality rate was 29%.

    Conclusions:

    • Early aggressive surgical debridement is the cornerstone of treatment.
    • Fluid administration and broad-spectrum antibiotics are initial therapeutic steps.
    • Understanding common presentations aids in prompt diagnosis and management of severe necrotizing infections.