Glycosylated plasma protein: a simple method for the elimination of interference by glucose in its estimation

Interference by glucose in the colorimetric estimation of glycosylated plasma protein was effectively eliminated by the precipitation of the proteins with trichloroacetic acid. The procedure was rapid and the recovery of protein quantitative. Results were highly reproducible. Preliminary clinical data obtained using the modified procedure showed rapid reflection by glycosylated plasma protein of the short-term control of glucose levels in diabetics when glycosylated haemoglobin values failed to indicate changes.