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The dentition in the osteogenesis imperfecta syndromes
Clinical Orthopaedics and Related Research
|September 1, 1981
Summary
Osteogenesis imperfecta (OI) can cause blue or brown opalescent teeth with abnormal dentin, leading to early wear. Dental evaluation upon tooth eruption is crucial for managing OI-related dental issues.
Area of Science:
- Dentistry
- Genetics
- Oral Medicine
Background:
- Osteogenesis imperfecta (OI) is a group of genetic disorders characterized by bone fragility.
- Dental anomalies, including opalescent teeth, are observed in some individuals with OI.
- These dental findings suggest potential genetic heterogeneity within OI syndromes.
Purpose of the Study:
- To describe the clinical and radiologic characteristics of opalescent teeth in osteogenesis imperfecta.
- To explore the relationship between dental anomalies and genetic heterogeneity in OI.
- To provide guidance for the dental management of patients with OI.
Main Methods:
- Clinical examination of deciduous and permanent dentitions.
- Radiologic assessment of pulp chambers, root canals, and tooth structure.
- Analysis of dental wear patterns and enamel integrity.
- Correlation of dental findings with fracture history and physical deformity.
Main Results:
- Opalescent teeth in OI patients range in color from blue to brown.
- Radiologic findings include obliterated pulp chambers/root canals and constricted crown-root junctions.
- Deciduous opalescent teeth exhibit rapid enamel loss and wear; permanent teeth are more resistant.
- No direct correlation found between fracture severity and dental anomaly degree.
- Normal dentition occurs in some OI patients, supporting genetic heterogeneity.
Conclusions:
- Clinical variations in dentition support genetic heterogeneity in osteogenesis imperfecta.
- Early dental evaluation is recommended for patients with OI and opalescent teeth.
- Further research is needed to establish optimal dental care protocols for OI patients.