Selective, immunologically nonspecific adherence of lymphoid and myeloid cells to Leydig cells

In mixed lymphocyte-testis cell cultures, lymphoid cells form rosettes around a testis cell population. The rosette formation seems to reflect cell type specific, but not immune recognition, because: a) rosettes are formed only around Leydig, But not around other testis cells; b) most, if not all normal lymphoid cells can be bound by Leydig cells; c) in addition, Leydig cells bind presumably monoclonal lymphoid and myeloid tumor line cells, but no other cell types.