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Updated: Aug 6, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Changes of left ventricular contractility in alternating left bundle branch block

G Baduini, G Calcaterra, P Rossi

    European Journal of Cardiology
    |January 1, 1981
    PubMed

    Insights

    This case study reports intermittent left bundle branch block causing alternating heart contractility in a borderline heart. The findings suggest peripheral block location may reduce left ventricular contractility.

    Area of Science:

    • Cardiology
    • Electrophysiology
    • Cardiac Physiology

    Background:

    • Left bundle branch block (LBBB) can affect cardiac function.
    • Understanding contractility changes in LBBB is crucial for patient management.

    Observation:

    • A case of intermittent, non-rate-dependent left bundle branch block is presented.
    • Alternating contractility indices (dP/dt, dP/dt/P) were observed.
    • The patient had a borderline normal heart function.

    Findings:

    • Reduced left ventricular contractility was noted during LBBB episodes.
    • This reduction may differ from findings by other authors.
    • A peripheral location of the left bundle branch block is hypothesized as the cause.

    Implications:

    • Peripheral LBBB may uniquely impact left ventricular contractility.
    • Further research is needed to confirm the relationship between block location and contractility.
    • This case highlights the complexity of LBBB in borderline cardiac conditions.

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