[The Laferma reflux family, a case of multiple familial reflux]

We substantiate that five of total seven examined members of a family including the mother showed a reflux disease. Two of them had a monolateral, three a bilateral, two a vesicoureteral and three a vesicorenal reflux. Three of the examined members suffered from enuresis nocturna. All of the reflux-positive members of the family endoscopically showed gaping ostia of the ureter at the reflux-positive side. We found no criteria for an intravesical obstruction. All reflux-positive members showed a low-pressure reflux. Interestingly, only the female members exhibited a reflux. We don't know whether this case of an increased incidence of reflux disease within one family will represent a known hereditary pattern.