Related Experiment Video
Updated: Aug 17, 2026

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
Published on: January 30, 2017
An outbreak of influenza B in an elderly population
Abstract:
An outbreak of influenza B occurred in an elderly population residing in a Minnesota nursing home between April 24 and May 21, 1979 and involved 129 (35.9%) of the 359 residents. Throat swabs from 11 and 19 acutely ill residents yielded influenza B virus similar to the B/Singapore/79 strain. Fourfold or greater increases in titer of complement-fixing or hemagglutination-inhibiting antibodies were detected in paired sera from 18 of the 19 persons affected and from three of 16 unaffected residents. Three hundred thirty-three (93%) of the 359 residents had received trivalent influenza virus vaccine in November 1978. The attack rate was age-specific and increased with age (z = 2.69; P = 0.007). Increasing susceptibility to influenza B with age in the elderly has not been previously demonstrated in this infrequently studied population. Increased risk for becoming ill was also found to be statistically associated with decreasing levels of care required and residence in closed wards and temporally associated with taking meals in the facility's dining areas.
Insights
An influenza B outbreak in a nursing home showed higher infection rates in older adults. This study highlights age-related susceptibility in the elderly to influenza B, even after vaccination.
Area of Science:
- Epidemiology
- Virology
- Gerontology
Background:
- Influenza B outbreaks can significantly impact vulnerable populations like the elderly in long-term care facilities.
- Understanding age-specific risks and contributing factors is crucial for effective public health interventions.
Purpose of the Study:
- To investigate an influenza B outbreak in a Minnesota nursing home.
- To determine the attack rate, identify the causative strain, and analyze risk factors associated with illness in the elderly population.
Main Methods:
- Case identification through clinical observation and laboratory confirmation (throat swabs, serology).
- Analysis of resident demographics, vaccination status, and living conditions.
- Statistical analysis to assess age-specific attack rates and risk factors.
Main Results:
- 129 out of 359 residents were infected with an influenza B strain similar to B/Singapore/79.
- The attack rate increased significantly with age, indicating age-specific susceptibility.
- Factors such as lower required care levels, closed ward residence, and dining hall meals were associated with increased illness risk.
Conclusions:
- The study demonstrates increasing susceptibility to influenza B with age in the elderly, a previously under-documented finding in this population.
- Vaccination status did not fully prevent infection, suggesting the need for enhanced preventive strategies in nursing homes.
- Environmental and care-related factors may also play a role in influenza transmission within institutional settings.
More Related Videos
Related Concept Videos
Vaccinations
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Infectious Diseases and Their Occurrence
Investigation of Disease Outbreaks
Arboviral Encephalitis
Influenza

