[Relation between the wall structure and modifications of the blood content (author's transl)]

In view of its anatomical position, physical characteristics and metabolism, the endothelial cell plays a major part in maintaining the integrity of the vascular system and in the relation between the blood content, both plasma and blood cells, and the wall structure. Where this continuous single layer undergoes anatomical or functional changes, a new equilibrium is set up, an equilibrium which is multifactorial and dynamic. It is governed by the vascular and blood components and by their interrelation; it varies as a function of time and of the biorheological conditions. The interrelationship between the blood content and the wall plays an important part in vascular pathology, especially of the degenerative and thrombotic type. A better understanding of these factors will enhance the possibility of preventing atherogenesis and lay the basis for a coherent and effective therapeutic attitude thrombosis.