Related Experiment Video
Updated: Aug 19, 2026

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
Published on: April 1, 2015
[Erythrocyte coagulating and fibrinolytic activity in chronic ischemic heart disease]
It is shown that the erythrocytes of patients suffering from chronic ischaemic heart disease have normal or increased procoagulant, decreased anticoagulant and fibrinolytic activity, i.e. they enhance the increased coagulating and decrease the fibrinolytic potential of plasma in this group of patients. Addition of syncumar to the combined treatment causes certain decrease of the erythrocyte hypercoagulation potential, though it still remains marked. The fibrinolytic activity of plasma and erythrocytes remains unchanged.
It is shown that the erythrocytes of patients suffering from chronic ischaemic heart disease have normal or increased procoagulant, decreased anticoagulant and fibrinolytic activity, i.e. they enhance the increased coagulating and decrease the fibrinolytic potential of plasma in this group of patients. Addition of syncumar to the combined treatment causes certain decrease of the erythrocyte hypercoagulation potential, though it still remains marked. The fibrinolytic activity of plasma and erythrocytes remains unchanged.
More Related Videos
09:38A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
Published on: February 14, 2017
08:01The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well
Published on: February 27, 2026
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Extrinsic and Intrinsic Pathways of Hemostasis
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Clot Retraction and Fibrinolysis
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations