Severe sensorineural deafness in children due to perforation of the round-window membrane

Lancet (London, England)
|November 12, 1977
PubMed

Insights

Round-window membrane perforation can occur in children with severe sensorineural hearing loss. Simple surgical repair led to a slight hearing improvement in all three cases studied.

Area of Science:

  • Otolaryngology
  • Pediatric Audiology
  • Neurosurgery

Background:

  • Sensorineural hearing loss (SNHL) is a significant auditory impairment in children.
  • The round-window membrane (RWM) plays a crucial role in cochlear mechanics and hearing.
  • RWM integrity is vital for maintaining inner ear fluid dynamics.

Observation:

  • Three pediatric patients presented with severe SNHL.
  • Diagnostic evaluation revealed perforation of the round-window membrane in all three children.
  • The perforations were identified as a potential cause or contributing factor to the hearing loss.

Findings:

  • A simple surgical repair technique was employed to address the RWM perforations.
  • Following the repair, all three children demonstrated a measurable, albeit small, improvement in their hearing thresholds.
  • Audiological assessments confirmed the positive impact of the intervention on auditory function.

Implications:

  • This study suggests that RWM perforation is a treatable condition in pediatric SNHL.
  • Simple surgical repair of RWM perforations may offer a viable therapeutic option for select cases.
  • Further research is warranted to explore the long-term efficacy and broader applicability of this repair technique in managing pediatric hearing loss.

Related Concept Videos

The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
Unrenewable Cells00:50

Unrenewable Cells

In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of their outer...
The Auditory Ossicles01:11

The Auditory Ossicles

The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
Anatomy of the Ear01:16

Anatomy of the Ear

Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
Auditory Pathway01:15

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
Perceiving Loudness, Pitch, and Location01:21

Perceiving Loudness, Pitch, and Location

The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...