[Prevention and treatment of the suppurative complications of severe mechanical trauma]

A curative mixture (contrical, hydrocortisone, chloramphenicol-succinate) was tested by the authors for the local or intraosseous introduction as blockades in 11 patients with severe mechanical injuries. Thirty eight patients with good outcomes of shock without hormonal drugs and 23 healthy donors were taken as control. It was established that massive doses of glucocorticosteroids during the first day after the injury exercised a regulating effect upon the dynamics of the cellular and humoral immunity.