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[Treatment of septicopyemic forms of acute hematogenic osteomyelitis using dimexide and hyperbaric oxygenation]
Vestnik Khirurgii Imeni I. I. Grekova
|July 1, 1981
Insights
Dimethyl sulfoxide (DMSO) and hyperbaric oxygen therapy (HBOT) effectively treated septicemic osteomyelitis in children. This combined approach improved patient outcomes, reduced swelling, and accelerated bone healing.
Area of Science:
- Orthopedics
- Infectious Diseases
- Regenerative Medicine
Context:
- Septicopyemic forms of acute hematogenic osteomyelitis present significant treatment challenges.
- Pediatric patients with severe bone infections require innovative therapeutic strategies.
Purpose:
- To evaluate the efficacy of a combined therapeutic approach using Dimexide (dimethyl sulfoxide) and hyperbaric oxygen therapy (HBOT) for septicopyemic acute hematogenic osteomyelitis.
- To assess the impact of this combined therapy on clinical and biochemical parameters in pediatric patients.
Summary:
- The study involved 54 pediatric patients diagnosed with septicopyemic acute hematogenic osteomyelitis.
- Patients received a curative complex incorporating Dimexide and HBOT.
- Treatment outcomes were assessed based on general patient condition, tissue edema, osseous tissue repair, and blood indices.
Impact:
- The integrated treatment regimen demonstrated significant effectiveness in managing severe osteomyelitis.
- Observed improvements include enhanced general health, reduced tissue edema, stimulated bone repair processes, and normalized blood parameters.
- This approach offers a promising strategy for improving recovery and reducing complications in pediatric osteomyelitis.
Abstract:
Dimexide and HBO-therapy were included in the curative complex for 54 patients with septicopyemic forms of acute hematogenic osteomyelitis, The authors' recommendations proved to be effective which was demonstrated by better general state of the children, less edema of tissues, stimulation of reparative processes of the osseous tissue in the injury zone, normalization of general and biochemical indices of blood.