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An easy-to-use maximum-likelihood method of estimating the ascertainment probability
American Journal of Human Genetics
|September 1, 1981
Abstract:
An easy-to-compute statistic for estimating the ascertainment probability is proposed. This statistic is determined through the use of the maximum-likelihood principle and, therefore, in addition to being easy to compute, has the desirable properties of a maximum-likelihood statistic. Variance tables are given to facilitate computation of the estimate and its variance.