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Pseudotumor cerebri: an observation and review
Annals of Ophthalmology
|July 1, 1981
Summary
Elevated erythrocyte sedimentation rate (ESR) correlated with papilledema in pseudotumor cerebri cases. Serial ESR measurements may help monitor this condition.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Pseudotumor cerebri (idiopathic intracranial hypertension) is a neurological disorder characterized by increased intracranial pressure.
- Papilledema, or optic nerve swelling, is a common sign of increased intracranial pressure.
Observation:
- In five consecutive patients diagnosed with pseudotumor cerebri, an elevated erythrocyte sedimentation rate (ESR) was consistently observed.
- This elevation in ESR demonstrated a correlation with the severity of papilledema.
Findings:
- Extensive medical investigations ruled out other potential causes for the elevated ESR in these patients.
- The erythrocyte sedimentation rate appears to be a potential biomarker in pseudotumor cerebri.
Implications:
- Serial ESR determinations could serve as a valuable, non-invasive tool for monitoring disease activity and treatment response in pseudotumor cerebri.
- Further research is warranted to validate ESR as a routine monitoring parameter for idiopathic intracranial hypertension.