[Cytospectrophotometry in the grading of malignant breast tumors]

The nuclear DNA content of neoplastic cell was measured in 30 cases of carcinomas of the human breast. The normal lymphocyte was used as a reference for the DNA value corresponding to a diploid number of chromosomes. Samples from the same cases were embedded in paraffin and stained with haematoxylin and eosin. The nuclear DNA content is compared with the histological malignancy grading following Bloom and Richardson.