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A simple device for ultrafiltration of serum under controlled pH
Clinical Biochemistry
|June 1, 1981
Summary
A new device efficiently produces serum ultrafiltrates at controlled pH levels. This innovation aids in obtaining accurate physiological measurements from human serum samples.
Area of Science:
- Biochemistry
- Medical Devices
- Analytical Chemistry
Background:
- Accurate serum ultrafiltrate preparation is crucial for biochemical analysis.
- Existing methods may lack precise pH control, affecting results.
- Controlled pH is essential for maintaining protein structure and function in ultrafiltrates.
Purpose of the Study:
- To describe a novel, simple device for producing serum ultrafiltrates.
- To demonstrate the device's capability for controlled pH conditions.
- To report initial findings from testing the device on normal human subjects.
Main Methods:
- Development of a simple apparatus for serum ultrafiltration.
- Implementation of pH monitoring and control within the device.
- Testing the device using serum samples from normal human subjects.
Main Results:
- The device successfully produced serum ultrafiltrates.
- Consistent pH control was achieved during the ultrafiltration process.
- Reported values from normal human subjects are presented.
Conclusions:
- The described device offers a straightforward method for controlled serum ultrafiltration.
- This tool facilitates reliable biochemical analyses by ensuring stable pH.
- Further application in clinical diagnostics and research is suggested.