Related Experiment Video
Updated: May 5, 2026
10:27
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
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Summary
Adult celiac disease can present with significant lymphadenopathy, a key clinical indicator. Peripheral lymphocytosis may also occur and fluctuate with celiac disease treatment.
Area of Science:
- Gastroenterology
- Immunology
- Hematology
Background:
- Celiac disease is an autoimmune disorder triggered by gluten ingestion.
- It primarily affects the small intestine but can manifest with diverse extraintestinal symptoms.
Observation:
- Two adult cases of celiac disease presented with prominent lymphadenopathy as the main clinical sign.
- One patient exhibited peripheral lymphocytosis that correlated with the management of their celiac disease.
Findings:
- Marked lymphadenopathy can be a significant, albeit uncommon, clinical manifestation of adult celiac disease.
- Peripheral lymphocytosis is a potential hematological finding in celiac disease, responsive to treatment.
Implications:
- Highlights the importance of considering celiac disease in adults presenting with unexplained lymphadenopathy.
- Suggests that lymphadenopathy and lymphocytosis may serve as indicators of disease activity or treatment response in celiac disease.
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