Treatment of chronic erosive gastritis with prednisolone

Short-term oral prednisolone was successfully used in the treatment of four patients with chronic erosive gastritis which had failed to respond to conventional therapies. Symptomatic improvement occurred in all patients during the first week of treatment. Gastroduodenoscopy after two weeks showed that the erosions had healed. Remission has continued in these four patients for two, seven, eight, and nine months without maintenance therapy. This limited uncontrolled study suggests the corticosteroids may be of benefit in patients with chronic erosive gastritis who fail to respond to conventional treatment.