[Liver biopsy findings in neurologic diseases with special reference to multiple sclerosis]

The histological results of 112 blind liver biopsies in eight etiologically different neurological diseases are reported in which there was no clinically obvious reason for suspecting a liver disease. An unexpectedly high level of morphological liver changes were found in primary diseases of the central nervous system on one hand, which, on the other showed no specificity for a particular neurological disease group. A direct conclusion on the genesis of the individual neurological disease is, however, not possible from the histopathological picture. If one compares the results of the multiple sclerosis patients with these of patients with other neurological diseases there is a great similarity with the myatrophic lateral sclerosis but also with the infectious diseases of the central nervous system.