[Comparative studies of the pressure-lowering effect of timolol and phospholine iodide (author's transl)]

A comparative study of the intraocular pressure-lowering effects of timolol and phospholine iodide in cases of aphakic glaucoma was carried out. The authors compared the I.O.P.-lowering effect of these two drugs in 30 eyes (30 patients) with aphakic glaucoma over an eight-month observation period. The following was established after a statistical analysis of the material: 1. The I.O.P.-lowering effect of timolol in aphakic glaucoma cases is almost identical with the effect of the drug in cases of chronic open-angle glaucoma. 2. The administration of phospholine iodide in such cases leads to a stable I.O.P. regulation and it seems that this therapy should be preferred to treatment with timolol. 3. Timolol therapy in cases of aphakic glaucoma should be considered an enrichment of the known treatment methods. 4. The administration of timolol requires constant follow-up and if this is not possible therapy with pilocarpine or phospholine iodide should be preferred.