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[Disturbances in coronary microcirculation (author's transl)]
Summary
Coronary insufficiency with normal coronary arteriograms often involves microcirculation issues. Advanced diagnostics can detect and treat these underlying vascular, rheological, and metabolic disorders.
Area of Science:
- Cardiology
- Vascular Medicine
- Diagnostic Imaging
Context:
- Coronary insufficiency with normal coronary arteriograms affects 10-20% of patients with exercise-induced symptoms.
- These cases frequently involve disturbances in coronary microcirculation.
Purpose:
- To explore the causes and diagnostic approaches for coronary insufficiency despite normal coronary arteriograms.
- To highlight the role of microcirculatory dysfunction in this clinical syndrome.
Summary:
- Microcirculatory disturbances underlying coronary insufficiency can stem from vascular diseases, rheological disorders, or impaired oxygen transport.
- Diagnosis utilizes traditional methods (ECG, stress tests) alongside advanced functional assessments (coronary blood flow, reserve, viscosity, serology, histology).
Impact:
- Detecting and treating microcirculatory issues offers a rational basis for managing persistent angina pectoris.
- This underscores the importance of advanced diagnostics for functional and therapeutic assessment of coronary microcirculation.